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APC Anti-Human CD54 Antibody [15.2] (AGEL2810)

Datasheet MSDS
SKU AGEL2810
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone 15.2
Conjugation APC
€98 - €390

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Description

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APC Anti-Human CD54 Antibody [15.2]

The APC Anti-Human CD54 Antibody (15-2) from Assay Genie is a high-quality research tool designed for studying CD54, a cell surface glycoprotein involved in cell adhesion and immune response regulation. This antibody is specifically engineered for use in flow cytometry applications and is highly reactive with human samples.CD54, also known as intercellular adhesion molecule-1 (ICAM-1), plays a vital role in mediating cell-to-cell interactions, particularly in immune responses such as leukocyte adhesion and migration. Its expression can be induced by inflammatory stimuli, making it a key player in the immune signaling cascade.

The APC Anti-Human CD54 Antibody (15-2) allows for the precise detection and analysis of CD54 expression in various cell types, making it an invaluable tool for research in immunology, inflammation, and infectious diseases.By targeting CD54, researchers can gain insights into the molecular mechanisms underlying immune responses and inflammatory processes, paving the way for the development of novel therapeutic strategies. The use of the APC Anti-Human CD54 Antibody (15-2) from Assay Genie ensures reliable and accurate results, making it an essential component of studies investigating the role of CD54 in health and disease.

Product Title:APC Anti-Human CD54 Antibody [15.2]
SKU:AGEL2810
Size:20 Tests, 100 Tests, 200 Tests
Clone No:15.2
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05362
Gene ID:3383
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.
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