Apoa1 Antibody (PACO64139)
- SKU:
- PACO64139
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Apoa1 Antibody (PACO64139) |
| Antibody SKU: | PACO64139 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:1000-1:5000 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Apoa1 protein (19-259AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat Heart tissue, Rat Liver tissue, Rat Spleen tissue, Rat Lung tissue, Rat Kidney tissue, Rat Brain tissue, Rat Stomach tissue. All lanes: Apoa1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa. |
| Background: | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Synonyms: | Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I)], Apoa1 |
| UniProt Protein Function: | Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| UniProt Protein Details: | Subunit structure: Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin Subcellular location: Secreted. Tissue specificity: Major protein of plasma HDL, also found in chylomicrons. Post-translational modification: Phosphorylation sites are present in the extracelllular medium Sequence similarities: Belongs to the apolipoprotein A1/A4/E family. |
| NCBI Summary: | major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase (LCAT) [RGD] |
| UniProt Code: | P04639 |
| NCBI GenInfo Identifier: | 6978515 |
| NCBI Gene ID: | 25081 |
| NCBI Accession: | NP_036870.1 |
| UniProt Secondary Accession: | P04639,O08877, O09054, Q5EBB2, |
| UniProt Related Accession: | P04639 |
| Molecular Weight: | |
| NCBI Full Name: | apolipoprotein A-I preproprotein |
| NCBI Synonym Full Names: | apolipoprotein A-I |
| NCBI Official Symbol: | Apoa1Â Â |
| NCBI Official Synonym Symbols: | apoA-IÂ Â |
| NCBI Protein Information: | apolipoprotein A-I; apo-AI; apolipoprotein A1; apolipoprotein A-1; preproapolipoprotein A-I |
| UniProt Protein Name: | Apolipoprotein A-I |
| UniProt Synonym Protein Names: | Apolipoprotein A1 |
| Protein Family: | Apolipoprotein |
| UniProt Gene Name: | Apoa1Â Â |
| UniProt Entry Name: | APOA1_RAT |
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