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ARHGEF7 Rabbit Polyclonal Antibody (CAB1108)

SKU:
CAB1108
Product Type:
Antibody
Reactivity:
Human
Mouse
Monkey
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ARHGEF7 Rabbit Polyclonal Antibody
SKU:CAB1108
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1).
Sequence:MNSA EQTV TWLI TLGV LESP KKTI SDPE GFLQ ASLK DGVV LCRL LERL LPGT IEKT FDAN DLYQ GQNF NKVL SSLV TLNK VTAD IGLG SDSV CARP SSHR IKSF DSLG SQSL HTRT SKLF QGQY RSLD MTDN SNNQ LVVR AKFN FQQT NEDE LSFS KGDV IHVT RVEE GGWW EGTL NGRT GWFP SNYV REVK ASEK PVSP KSGT LKSP PKGF DTTA INKS YYNV VLQN ILET ENEY SKEL QTVL STYL RPLQ TSEK LSSA
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314; ARHGEF7
Positive Sample:SW620,Jurkat,COS-1,COS-7,MCF7,K-562,Mouse lung,Mouse heart
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell projection, Cytoplasm, cell cortex, focal adhesion, lamellipodium, ruffle.
Calculated MW:90kDa
Observed MW:86kDa

This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Purification Method:Affinity purification
Gene ID:8874
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using ARHGEF7 antibody (CAB1108) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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