The ARL8B Antibody (CAB8869) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive with human, mouse, and rat samples, making it versatile for a variety of experimental applications.ARL8B is a member of the ADP-ribosylation factor-like family and is known to be involved in processes such as endocytic trafficking, phagosome maturation, and autophagy. By targeting ARL8B, researchers can study its function in these cellular processes and gain insights into its potential role in diseases like cancer, neurodegenerative disorders, and infectious diseases.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
ARL8B Antibody
SKU:
CAB8869
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cytoplasm, Late Endosome Membrane, Lysosome Membrane, Cytoskeleton, Spindle.
Calculated MW:
22kDa
Observed MW:
21kDa
Enables guanyl ribonucleotide binding activity and tubulin binding activity. Involved in several processes, including calcium ion regulated lysosome exocytosis; lysosomal transport; and vesicle fusion. Located in cytolytic granule membrane; midbody; and spindle midzone. Colocalizes with lysosomal membrane.
Purification Method
Affinity purification
Gene ID
55207
RRID
AB_2768446
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARL8B Rabbit pAb (CAB8869) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 30s.
Confocal immunofluorescence analysis of U2OS cells using ARL8B Rabbit pAb (CAB8869) at dilution of 1:100. Blue: DAPI for nuclear staining.
