The BANK1 Antibody (CAB10312) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is specifically tailored to detect BANK1 in human samples and is validated for use in Western blot applications. By binding to the BANK1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for immunology and autoimmune research studies.BANK1, also known as B-cell scaffold protein with ankyrin repeats 1, plays a crucial role in B-cell receptor signaling and immune response modulation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
BANK1 Antibody
SKU:
CAB10312
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BANK, BANK1
Positive Sample:
B cells, Raji, U-87MG, A-549, 22Rv1, HepG2, Mouse liver, Rat liver
Cellular Localization:
Perinuclear Region Of Cytoplasm.
Calculated MW:
89kDa
Observed MW:
89kDa
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
55024
RRID
AB_2757856
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using BANK1 Rabbit pAb (CAB10312) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
