The CD239/BCAM Antibody (CAB14747) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and specifically targets the BCAM protein in human samples, making it ideal for use in Western blot applications.BCAM is a cell surface molecule that plays a key role in cell adhesion and is involved in processes such as cell migration, signaling, and development. It is particularly important in the context of blood cell interactions and vascular biology, making it a valuable target for research in areas such as hematology, vascular biology, and cancer research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
CD239/BCAM Antibody
SKU:
CAB14747
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AU, LU, CD239, MSK19, CD239/BCAM
Positive Sample:
Mouse lung
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
67kDa
Observed MW:
90kDa
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
4059
RRID
AB_2761624
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using CD239/BCAM Rabbit pAb (CAB14747) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
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