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Bid Rabbit Polyclonal Antibody (CAB0210)

SKU:
CAB0210
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-Bid Antibody CAB0210
  • Cell Death Antibodies 1 Anti-Bid Antibody CAB0210
  • Cell Death Antibodies 1 Anti-Bid Antibody CAB0210
  • Cell Death Antibodies 1 Anti-Bid Antibody CAB0210
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Bid Rabbit Polyclonal Antibody
SKU:CAB0210
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human Bid (NP_001187.1).
Sequence:MDCE VNNG SSLR DECI TNLL VFGF LQSC SDNS FRRE LDAL GHEL PVLA PQWE GYDE LQTD GNRS SHSR LGRI EADS ESQE DIIR NIAR HLAQ VGDS MDRS IPPG LVNG LALQ LRNT SRSE EDRN RDLA TALE QLLQ AYPR DMEK EKTM LVLA LLLA KKVA SHTP SLLR DVFH TTVN FINQ NLRT YVRS LARN GMD
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:FP497; Bid
Positive Sample:Jurkat,Rat thymus,Mouse liver,Mouse heart,293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion membrane, Mitochondrion membrane.
Calculated MW:22kDa
Observed MW:20kDa//15kDa

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found.

Purification Method:Affinity purification
Gene ID:637
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Jurkat cells, using Bid Rabbit pAb (CAB0210) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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