The Biotinylated Anti-BTN3A1 Antibody (HDLA054) is a valuable tool for research involving BTN3A1, a cell surface protein involved in immune regulation and activation. This antibody, produced in-house and rigorously validated, is highly specific for BTN3A1 and is ideal for use in various applications such as immunofluorescence, flow cytometry, and immunoprecipitation.BTN3A1, also known as CD277, is a member of the B7 family of immune checkpoint molecules and plays a crucial role in modulating immune responses. It has been implicated in the regulation of T cell activation and proliferation, making it a promising target for immunotherapy and cancer research.
By targeting BTN3A1, researchers can gain insights into the mechanisms of immune regulation and potentially develop novel therapies for cancer and other immune-related disorders.Overall, the Biotinylated Anti-BTN3A1 Antibody (HDLA054) offers researchers a reliable and specific tool for studying BTN3A1 and its role in immune modulation, making it a valuable asset for studies in immunology, oncology, and related fields.
Product Code:
HDLA054
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM92
Synonyms:
BTN3A1, BTF5, CD277, BTN3.1, BT3.1
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each.
