The Biotinylated Anti-CD27 Antibody (HDLA022) is a highly specific and sensitive tool for researchers studying the CD27 cell surface molecule. This antibody, generated using cutting-edge technology, is designed for use in experiments such as flow cytometry, immunohistochemistry, and ELISA.CD27, a member of the tumor necrosis factor receptor superfamily, is a crucial regulator of immune responses and plays a vital role in the development and differentiation of immune cells. The Biotinylated Anti-CD27 Antibody binds specifically to CD27, allowing for accurate and reliable detection and analysis in various sample types.
Researchers in immunology, oncology, and infectious diseases will find this antibody particularly useful for investigating the role of CD27 in immune cell activation, differentiation, and memory formation. By understanding the function of CD27, scientists can gain insights into diseases such as cancer, viral infections, and autoimmune disorders, potentially leading to the development of novel therapeutic strategies. Trust in the Biotinylated Anti-CD27 Antibody (HDLA022) for high-quality, reproducible results in your research endeavors.
Product Code:
HDLA022
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM59
Synonyms:
CD27, TNFRSF7, S152, T14, Tp55
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
