The Biotinylated Anti-CD38 Antibody (HDLA004) is a valuable tool for researchers studying CD38, a cell surface protein involved in immune regulation and cell signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in various applications such as immunofluorescence and flow cytometry.CD38 is known to play a role in immune responses and is a potential target for therapies aimed at modulating immune function in diseases like cancer and autoimmune disorders. The Biotinylated Anti-CD38 Antibody allows for the specific detection and analysis of CD38 expression in different cell types, offering insights into its function and potential therapeutic applications.
By utilizing this antibody, researchers can further investigate the role of CD38 in immune regulation and disease pathogenesis, paving the way for improved treatments and therapies in the field of immunology and cancer research. Get your hands on the Biotinylated Anti-CD38 Antibody (HDLA004) today to advance your research efforts in these critical areas.
Product Code:
HDLA004
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM30
Synonyms:
T10, cADPr hydrolase 1
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
