The Biotinylated Anti-CD38 Antibody (HDLA002) is a powerful tool for researchers studying CD38, a cell surface protein involved in immune response regulation and signaling. This antibody, produced through advanced biotinylation techniques, exhibits high specificity and sensitivity in detecting CD38 in human samples. Validated for use in various applications including immunofluorescence and flow cytometry, the Biotinylated Anti-CD38 Antibody (HDLA002) enables precise and accurate detection of CD38 expression in different cell types and tissues.
Its versatility makes it an essential component in immunology research, cancer studies, and investigations into autoimmune and inflammatory disorders. By targeting CD38, researchers can gain valuable insights into immune cell function, disease mechanisms, and potential therapeutic interventions. The Biotinylated Anti-CD38 Antibody (HDLA002) is a valuable tool for advancing scientific understanding and developing novel treatments in the fields of immunology and oncology.
SKU:
HDLA002
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM28
Synonyms:
T10, cADPr hydrolase 1
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
