The Bovine Sarcoplasmic Endoplasmic Reticulum Calcium ATPase 1 (ATP2A1) ELISA Kit is a cutting-edge assay designed for the precise measurement of ATP2A1 levels in bovine samples. This kit offers exceptional sensitivity and specificity, ensuring accurate and consistent results for a variety of research applications.ATP2A1, also known as SERCA1, is a crucial enzyme responsible for calcium transport in muscle cells.
Dysregulation of ATP2A1 has been linked to various muscle disorders, making it a valuable biomarker for studying muscle function and diseases. This ELISA kit provides researchers with a reliable tool to explore the role of ATP2A1 in muscle physiology and pathophysiology, offering insights into potential therapeutic strategies for muscle-related conditions.
Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, SERCA1
Assay Type:
Competitive
Detection Method:
ELISA
Reactivity:
Bovine
Detection Range:
0.78-50ng/mL
Sensitivity:
0.27ng/mL
Intra CV:
Provided with the Kit
Inter CV:
Provided with the Kit
Linearity:
Provided with the Kit
Recovery:
Provided with the Kit
Function:
Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Uniprot:
Q0VCY0
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Specificity:
Natural and recombinant bovine Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Sub Unit:
Interacts with sarcolipin (SLN) (By similarity). Interacts with phospholamban (PLN) (By similarity). Interacts with myoregulin (MRLN). Interacts with DWORF.
Research Area:
Neurosciences
Subcellular Location:
Endoplasmic reticulum membrane Multi-pass membrane protein Sarcoplasmic reticulum membrane Multi-pass membrane protein
