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CACNA1E Rabbit Polyclonal Antibody (CAB10203)

SKU:
CAB10203
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CACNA1E Rabbit Polyclonal Antibody
SKU:CAB10203
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1).
Sequence:PSSM RRSF STIR DKRS NSSW LEEF SMER SSEN TYKS RRRS YHSS LRLS AHRL NSDS GHKS DTHR SGGR ERGR SKER KHLL SPDV SRCN SEER GTQA DWES PERR QSRS PSEG RSQT PNRQ GTGS LSES SIPS VSDT STPR RSRR QLPP VPPK PRPL LSYS SLIR HAGS ISPP ADGS EEGS PLTS QALE SNNA CLTE SSNS PHPQ QSQH ASPQ RYIS EPYL ALHE DSHA SDCG EEET LTFE AAVA TSLG RSNT IGSA PPLR HSWQ MPNG HYRR RRRG GPGP GMMC GAVN NLLS DTEE DDKC
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:BII; CACH6; DEE69; gm139; Cav2.3; EIEE69; CACNL1A6; CACNA1E
Positive Sample:U-87MG,293T,Mouse brain,Mouse liver,Rat brain
Conjugate:Unconjugated
Cellular Localization:Membrane, Multi-pass membrane protein.
Calculated MW:262kDa
Observed MW:290kDa

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:777
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using CACNA1E antibody (CAB10203) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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