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Anti-CADM3 Antibody (CAB4902)

SKU:
CAB4902
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CADM3
BIgR
IGSF4B
NECL1
Necl-1
TSLL1
synCAM3
Research Area:
Cell Biology
  • Cell Biology Antibodies 9 Anti-CADM3 Antibody CAB4902
  • Cell Biology Antibodies 9 Anti-CADM3 Antibody CAB4902
€139 - €419
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Description

Product Name:CADM3 Rabbit pAb
Product Code:CAB4902
Size:20uL, 50uL, 100uL
Synonyms:CADM3, BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, MCF7, HL-60, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NLSQ DDSQ PWTS DETV VAGG TVVL KCQV KDHE DSSL QWSN PAQQ TLYF GEKR ALRD NRIQ LVTS TPHE LSIS ISNV ALAD EGEY TCSI FTMP VRTA KSLV TVLG IPQK PIIT GYKS SLRE KDTA TLNC QSSG SKPA ARLT WRKG DQEL HGEP TRIQ EDPN GKTF TVSS SVTF QVTR EDDG ASIV CSVN HESL KGAD RSTS QRIE VLYT PTAM IRPD PPHP REGQ KLLL HCEG RGNP VPQQ YLWE KEGS VPPL KMTQ ESAL IFPF LNKS DSGT YGCT ATSN MGSY KAYY TLNV NDPS PVPS SSST YH
Gene ID:57863
Uniprot:Q8N126
Cellular Location:Cell junction, Cell membrane, Single-pass type I membrane protein
Calculated MW:38kDa/43kDa/47kDa
Observed MW:43kDa
UniProt Protein Function:CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.2-q22

Cellular Component: cell-cell adherens junction; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function:cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance; protein localization

NCBI Summary:IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008]
UniProt Code:Q8N126
NCBI GenInfo Identifier:74759761
NCBI Gene ID:57863
NCBI Accession:Q8N126.1
UniProt Secondary Accession:Q8N126,Q8IZQ9, Q9NVJ5, Q9UJP1,
UniProt Related Accession:Q8N126
Molecular Weight:38,326 Da
NCBI Full Name:Cell adhesion molecule 3
NCBI Synonym Full Names:cell adhesion molecule 3
NCBI Official Symbol:CADM3  
NCBI Official Synonym Symbols:BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3  
NCBI Protein Information:cell adhesion molecule 3
UniProt Protein Name:Cell adhesion molecule 3
UniProt Synonym Protein Names:Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1
Protein Family:Cell adhesion molecule
UniProt Gene Name:CADM3  
UniProt Entry Name:CADM3_HUMAN

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