| UniProt Protein Function: | CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.17; Kinase, protein; CAMK group; CAMK1 family Chromosomal Location of Human Ortholog: 5q21.3 Cellular Component: cytoplasm; cytosol; nucleolus; nucleoplasm Molecular Function:ATP binding; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity Biological Process: adaptive immune response; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; inflammatory response; innate immune response; long-term memory; myeloid dendritic cell cytokine production; myeloid dendritic cell differentiation; nerve growth factor receptor signaling pathway; nerve-nerve synaptic transmission; nucleocytoplasmic transport; peptidyl-serine phosphorylation; phospholipase C activation; positive regulation of protein export from nucleus; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of osteoclast differentiation; regulation of T cell differentiation in the thymus; signal transduction; synaptic transmission |
| NCBI Summary: | The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16566 |
| NCBI GenInfo Identifier: | 2499586 |
| NCBI Gene ID: | 814 |
| NCBI Accession: | Q16566.1 |
| UniProt Secondary Accession: | Q16566,D3DSZ7, |
| UniProt Related Accession: | Q16566 |
| Molecular Weight: | 51,926 Da |
| NCBI Full Name: | Calcium/calmodulin-dependent protein kinase type IV |
| NCBI Synonym Full Names: | calcium/calmodulin-dependent protein kinase IV |
| NCBI Official Symbol: | CAMK4Â Â |
| NCBI Official Synonym Symbols: | caMK; CaMK IV; CaMK-GRÂ Â |
| NCBI Protein Information: | calcium/calmodulin-dependent protein kinase type IV |
| UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase type IV |
| UniProt Synonym Protein Names: | CaM kinase-GR |
| Protein Family: | Calcium/calmodulin-dependent protein kinase |
| UniProt Gene Name: | CAMK4Â Â |
| UniProt Entry Name: | KCC4_HUMAN |
