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Anti-CAPN7 Antibody (CAB17666)

SKU:
CAB17666
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CAPN7 Antibody
Antibody SKU:CAB17666
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RDHE GRYS EAVF YYKE AAQA LIYA EMAG SSLE NIQE KITE YLER VQAL HSAV QSKS ADPL KSKH QLDL ERAH FLVT QAFD EDEK ENVE DAIE LYTE AVDL CLKT SYET ADKV LQNK LKQL ARQA LDRA EALS EPLT KPVG KISS TSVK PKPP PVRA HFPL GANP FLER PQSF ISPQ SCDA QGQR YTAE EIEV LRTT SKIN G
Gene ID:23473
Uniprot:Q9Y6W3
Cellular Location:
Calculated MW:92kDa
Observed MW:93kDa
Anti-CAPN7 Antibody (CAB17666)Western blot - CAPN7 Rabbit pAb (CAB17666)
Synonyms:CALPAIN7, PALBH, CAPN7, calpain-7
Background:Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]
UniProt Protein Function:Calcium-regulated non-lysosomal thiol-protease.
NCBI Summary:Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y6W3
NCBI GenInfo Identifier:7656959
NCBI Gene ID:23473
NCBI Accession:NP_055111.1
UniProt Related Accession:Q9Y6W3
Molecular Weight:
NCBI Full Name:calpain-7
NCBI Synonym Full Names:calpain 7
NCBI Official Symbol:CAPN7  
NCBI Official Synonym Symbols:PALBH; CALPAIN7  
NCBI Protein Information:calpain-7
UniProt Protein Name:Calpain-7
UniProt Synonym Protein Names:PalB homolog; PalBH
UniProt Gene Name:CAPN7  

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