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Cell Biology Antibodies 11 Anti-CBR3 Antibody CAB7545
Key Features

CBR3 Rabbit Polyclonal Antibody (CAB7545)

Datasheet MSDS
SKU CAB7545
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse, Rat
Host Species Rabbit
Synonyms hCBR3, SDR21C2, HEL-S-25, CBR3
Research Use Cell Biology
€96 - €370

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Description

system_update_altDatasheetsystem_update_altMSDS

CBR3 Antibody (CAB7545)

The CBR3 Antibody (CAB7545) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.CBR3, also known as carbonyl reductase 3, plays a vital role in drug metabolism and detoxification processes in the liver. Its expression levels have been linked to drug efficacy and toxicity, making it a target of interest in pharmacology and toxicology studies.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CBR3 Antibody
SKU:CAB7545
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TRNM CNEL LPIM KPHG RVVN ISSL QCLR AFEN CSED LQER FHSE TLTE GDLV DLMK KFVE DTKN EVHE REGW PNSP YGVS KLGV TVLS RILA RRLD EKRK ADRI LVNA CCPG PVKT DMDG KDSI RTVE EGAE TPVY LALL PPDA TEPQ GQLV HDKV VQNW
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:hCBR3, SDR21C2, HEL-S-25, CBR3
Positive Sample:SW480, NCI-H460, MCF7, BT-474, Mouse lung, Mouse brain, Mouse ovary, Rat brain
Cellular Localization:Cytoplasm.
Calculated MW:31kDa
Observed MW:31kDa

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Purification MethodAffinity purification
Gene ID874
RRIDAB_2768070
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBR3 Rabbit pAb (CAB7545) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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