Anti-CCT8 Antibody (CAB4449)
- SKU:
- CAB4449
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CCT8
- C21orf112
- Cctq
- D21S246
- PRED71
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | CCT8 Rabbit pAb |
| Product Code: | CAB4449 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CCT8, C21orf112, Cctq, D21S246, PRED71 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 248-497 of human CCT8 (NP_001269837.1). |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | B cells, LO2, 293T, HeLa, Mouse brain, Mouse liver, Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 248-497 of human CCT8 (NP_001269837.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DMAL HYAN KYNI MLVR LNSK WDLR RLCK TVGA TALP RLTP PVLE EMGH CDSV YLSE VGDT QVVV FKHE KEDG AIST IVLR GSTD NLMD DIER AVDD GVNT FKVL TRDK RLVP GGGA TEIE LAKQ ITSY GETC PGLE QYAI KKFA EAFE AIPR ALAE NSGV KANE VISK LYAV HQEG NKNV GLDI EAEV PAVK DMLE AGIL DTYL GKYW AIKL ATNA AVTV LRVD QIIM AKPA GGPK PPSG KKDW DDDQ ND |
| Gene ID: | 10694 |
| Uniprot: | P50990 |
| Cellular Location: | Cytoplasm, centrosome, cilium basal body, cytoskeleton, microtubule organizing center |
| Calculated MW: | 51kDa/57kDa/59kDa |
| Observed MW: | 60kDa |
| UniProt Protein Function: | CCT8: a chaperone of the TCP-1 chaperonin family. A part of a hetero-oligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Chaperone Chromosomal Location of Human Ortholog: 21q22.11 Cellular Component: centrosome; chaperonin-containing T-complex; cytoplasm; cytosol; intermediate filament cytoskeleton; microtubule; nucleoplasm Molecular Function:ATPase activity, coupled; protein binding Biological Process: positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization |
| NCBI Summary: | This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013] |
| UniProt Code: | P50990 |
| NCBI GenInfo Identifier: | 9988062 |
| NCBI Gene ID: | 10694 |
| NCBI Accession: | P50990.4 |
| UniProt Secondary Accession: | P50990,Q4VBP8, A6NN54, B4DEM7, B4DQH4, |
| UniProt Related Accession: | P50990 |
| Molecular Weight: | 51,586 Da |
| NCBI Full Name: | T-complex protein 1 subunit theta |
| NCBI Synonym Full Names: | chaperonin containing TCP1 subunit 8 |
| NCBI Official Symbol: | CCT8Â Â |
| NCBI Official Synonym Symbols: | Cctq; PRED71; D21S246; C21orf112Â Â |
| NCBI Protein Information: | T-complex protein 1 subunit theta |
| UniProt Protein Name: | T-complex protein 1 subunit theta |
| UniProt Synonym Protein Names: | CCT-theta; Renal carcinoma antigen NY-REN-15 |
| Protein Family: | Probable T-complex protein |
| UniProt Gene Name: | CCT8Â Â |
| UniProt Entry Name: | TCPQ_HUMAN |
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