CD45RO monoclonal antibody (FITC) (AGIM0321)

SKU:
AGIM0321
€145

Description

Technical Manual

Overview:

Title:CD45RO monoclonal antibody (FITC)
Background:CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells.
Host Species:Mouse
Isotype:IgG2a
Size:100 µl
Clone:UCHL1
Conjugation:FITC
Reactivity:Human
Tested Applications:FC, IF
Storage Conditions:Store at 4°C. Avoid prolonged exposure to light.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Product type:
Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
UCHL1
Conjugation:
FITC
Application:
FC
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