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CDK1 Rabbit Polyclonal Antibody (CAB12414)

SKU:
CAB12414
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-CDK1 Antibody CAB12414
  • Cell Death Antibodies 1 Anti-CDK1 Antibody CAB12414
  • Cell Death Antibodies 1 Anti-CDK1 Antibody CAB12414
  • Cell Death Antibodies 1 Anti-CDK1 Antibody CAB12414
  • Cell Death Antibodies 1 Anti-CDK1 Antibody CAB12414
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CDK1 Rabbit Polyclonal Antibody
SKU:CAB12414
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human CDK1 (NP_001777.1).
Sequence:MEDY TKIE KIGE GTYG VVYK GRHK TTGQ VVAM KKIR LESE EEGV PSTA IREI SLLK ELRH PNIV SLQD VLMQ DSRL YLIF EFLS MDLK KYLD SIPP GQYM DSSL VKSY LYQI LQGI VFCH SRRV LHRD LKPQ NLLI DDKG TIKL ADFG LARA FGIP IRVY THEV VTLW YRSP EVLL GSAR YSTP VDIW SIGT IFAE LATK KPLF HGDS EIDQ LFRI FRAL GTPN NEVW PEVE SLQD YKNT FPKW KPGS LASH VKNL DENG LDLL SKML IYDP AKRI SGKM ALNH PYFN DLDN QIKK M
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:CDC2; CDC28A; P34CDC2; CDK1
Positive Sample:HeLa,MCF7,Jurkat,Mouse spleen
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion, Nucleus, centrosome, cytoskeleton, microtubule organizing center, spindle.
Calculated MW:34kDa
Observed MW:34kDa

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:983
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CDK1 Rabbit pAb (CAB12414) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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