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Anti-CDC42EP3 Antibody (CAB8480)

SKU:
CAB8480
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

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Antibody Name:Anti-CDC42EP3 Antibody
Antibody SKU:CAB8480
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, K-562, NIH/3T3, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPAK TPIY LKAA NNKK GKKF KLRD ILSP DMIS PPLG DFRH TIHI GKEG QHDV FGDI SFLQ GNYE LLPG NQEK AHLG QFPG HNEF FRAN STSD SVFT ETPS PVLK NAIS LPTI GGSQ ALML PLLS PVTF NSKQ ESFG PAKL PRLS CEPV MEEK AQEK SSLL ENGT VHQG DTSW GSSG SASQ SSQG RDSH SSSL SEQY PDWP AEDM FDHP TPCE LIKG KTKS EESL SDLT GSLL SLQL DLGP SLLD EVLN VMDK NK
Gene ID:10602
Uniprot:Q9UKI2
Cellular Location:Cytoplasm, Endomembrane system, Peripheral membrane protein, cytoskeleton
Calculated MW:27kDa
Observed MW:37kDa
Synonyms:CDC42EP3, BORG2, CEP3, UB1
Background:This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
NCBI Summary:This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
UniProt Code:Q9UKI2
NCBI GenInfo Identifier:395627662
NCBI Gene ID:10602
NCBI Accession:NP_001257365.1
UniProt Secondary Accession:Q9UKI2,O95353, Q9UQJ0, B2R8S0,
UniProt Related Accession:Q9UKI2
Molecular Weight:27,678 Da
NCBI Full Name:cdc42 effector protein 3
NCBI Synonym Full Names:CDC42 effector protein 3
NCBI Official Symbol:CDC42EP3  
NCBI Official Synonym Symbols:UB1; CEP3; BORG2  
NCBI Protein Information:cdc42 effector protein 3
UniProt Protein Name:Cdc42 effector protein 3
UniProt Synonym Protein Names:Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein
UniProt Gene Name:CDC42EP3  
Anti-CDC42EP3 Polyclonal Antibody (CAB8480)Western blot analysis of extracts of various cell lines, using CDC42EP3 antibody (CAB8480) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

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