CDC45 Rabbit Polyclonal Antibody (CAB16032)
- SKU:
- CAB16032
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDC45 Rabbit Polyclonal Antibody |
SKU: | CAB16032 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-566 of human CDC45 (O75419). |
Sequence: | MFVS DFRK EFYE VVQS QRVL LFVA SDVD ALCA CKIL QALF QCDH VQYT LVPV SGWQ ELET AFLE HKEQ FHYF ILIN CGAN VDLL DILQ PDED TIFF VCDT HRPV NVVN VYND TQIK LLIK QDDD LEVP AYED IFRD EEED EEHS GNDS DGSE PSEK RTRL EEEI VEQT MRRR QRRE WEAR RRDI LFDY EQYE YHGT SSAM VMFE LAWM LSKD LNDM LWWA IVGL TDQW VQDK ITQM KYVT DVGV LQRH VSRH NHRN EDEE NTLS VDCT RISF EYDL RLVL YQHW SLHD SLCN TSYT AARF KLWS VHGQ KRLQ EFLA DMGL PLKQ VKQK FQAM DISL KENL REMI EESA NKFG MKDM RVQT FSIH FGFK HKFL ASDV VFAT MSLM ESPE KDGS GTDH FIQA LDSL SRSN LDKL YHGL ELAK KQLR ATQQ TIAS CLCT NLVI SQGP FLYC SLME GTPD VMLF SRPA SLSL LSKH LLKS FVCS TKNR RCKL LPLV MAAP LSME HGTV TVVG IPPE TDSS DRKN FFGR AFEK AAES TSSR MLHN HFDL SVIE LKAE DRSK FLDA LISL LS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CDC45L; MGORS7; CDC45L2; PORC-PI-1; CDC45 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 66kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8318 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |