The CEL Antibody (CAB13011) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to CEL in human samples and is suitable for use in Western blot applications. By binding to the CEL protein, this antibody allows for precise detection and analysis in various cell types, making it an essential reagent for studies in immunology and cancer research.CEL, also known as carboxyl ester lipase, plays a crucial role in lipid metabolism and digestion by catalyzing the hydrolysis of dietary fats.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
CEL Antibody
SKU:
CAB13011
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8, CEL
Positive Sample:
Mouse pancreas
Cellular Localization:
Secreted.
Calculated MW:
79kDa
Observed MW:
67kDa
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
Purification Method
Affinity purification
Gene ID
1056
RRID
AB_2759858
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse pancreas, using CEL Rabbit pAb (CAB13011) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
