The CHDH Antibody (CAB16545) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CHDH plays a crucial role in maintaining cellular function by catalyzing the conversion of choline to betaine, a process that is essential for lipid metabolism and DNA methylation. Dysregulation of CHDH activity has been implicated in various diseases, including cardiovascular disorders, liver disease, and metabolic syndromes.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CHDH Antibody
SKU:
CAB16545
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date.
Purification Method
Affinity purification
Gene ID
55349
RRID
AB_2768890
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using CHDH Rabbit pAb (CAB16545) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC):Jurkat Exposure time: 1s.
Immunohistochemistry analysis of paraffin-embedded Human kidney using CHDH Rabbit pAb (CAB16545) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
