Claudin 1 Rabbit Polyclonal Antibody (CAB2196)
- SKU:
- CAB2196
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Claudin 1 Rabbit Polyclonal Antibody |
SKU: | CAB2196 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 137-211 of human Claudin 1 (NP_066924.1). |
Sequence: | TAWY GNRI VQEF YDPM TPVN ARYE FGQA LFTG WAAA SLCL LGGA LLCC SCPR KTTS YPTP RPYP KPAP SSGK DYV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CLD1; SEMP1; ILVASC; Claudin 1 |
Positive Sample: | A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 23kDa |
Observed MW: | 20kDa |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Purification Method: | Affinity purification |
Gene ID: | 9076 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |