CLDN7 Rabbit Polyclonal Antibody (CAB2035)
- SKU:
- CAB2035
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CLDN7 Rabbit Polyclonal Antibody |
SKU: | CAB2035 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7 (NP_001298.3). |
Sequence: | QWQM SSYA GDNI ITAQ AMYK GLWM DCVT QSTG MMSC KMYD SVLA LSAA LQAT RALM VVSL VLGF LAMF VATM GMKC TRCG GDDK VKKA RIAM GGGI IFIV AGLA ALVA CSWY GHQI VTDF YNPL IPTN IKYE FGPA IFIG WAGS ALVI LGGA LLSC SCPG NESK AGYR VPRS YPKS NSSK EYV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:100 - 1:500 |
Synonyms: | CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1; CLDN7 |
Positive Sample: | Mouse large intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Lateral cell membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method: | Affinity purification |
Gene ID: | 1366 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |