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Clervonafusp Alfa (Research-Grade)
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Clervonafusp Alfa (Research-Grade) (GXBS02040)

Datasheet MSDS
SKU GXBS02040
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FCM, Functional assay, Research in vivo
Isotype IgG1-kappa (fused with Homo sapiens GAA/glucosidase alpha)
$751 - $2,507

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Description

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Clervonafusp Alfa (Research-Grade)

Clervonafusp Alfa (Research-Grade) is a research-grade biosimilar monoclonal antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research.

Product Name:Clervonafusp Alfa (Research-Grade)
SKU:GXBS02040
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Target:Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter
Isotype:IgG1-kappa (fused with Homo sapiens GAA/glucosidase alpha)
Host Species:Human
Reactivity:Human
Applications:ELISA, FCM, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:VAL-1221
Biological Activity:Lysosomal α-Glucosidase is a γ-amylase that is essential for the degradation of glycogen in lysosomes [1] [2].
Purity:>95% as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4.
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:Q14542 & P10253
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