The CSNK2A2 Polyclonal Antibody (CAB13481) is a valuable tool for researchers studying CSNK2A2, a gene encoding casein kinase II subunit alpha. This antibody, produced in rabbits, has been shown to have high reactivity with human samples and is suitable for use in Western blot applications. By binding to the CSNK2A2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell signaling pathways and cancer research.CSNK2A2, a member of the casein kinase II family, is involved in regulating various cellular processes such as cell growth, proliferation, and survival.
Dysregulation of CSNK2A2 has been implicated in cancers, making it a promising target for therapeutic interventions. By studying the role of CSNK2A2 in cancer development and progression, researchers can gain valuable insights into potential treatment strategies targeting this gene.Overall, the CSNK2A2 Polyclonal Antibody (CAB13481) is a reliable tool for researchers looking to further understand the functions of CSNK2A2 in both normal and disease states, ultimately contributing to advancements in cancer research and therapeutics.
Product Name:
CSNK2A2 Rabbit Polyclonal Antibody
SKU:
CAB13481
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CSNK2A2 (NP_001887.1).
This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11.
Purification Method:
Affinity purification
Gene ID:
1459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSNK2A2 Rabbit pAb (CAB13481) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
