The CSNK2A2 Polyclonal Antibody (CAB1616) is a specialized tool for researchers studying CSNK2A2, a protein kinase known to play a role in cell growth and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. With its ability to specifically bind to CSNK2A2, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for studies in cell biology and cancer research.
CSNK2A2, also known as casein kinase 2 alpha prime, is a critical regulator of diverse cellular processes including cell proliferation, apoptosis, and signal transduction. Its involvement in these pathways positions it as a potential therapeutic target in cancer and other diseases characterized by dysregulated cell growth. By understanding the function of CSNK2A2, researchers can uncover new insights into disease mechanisms and potentially develop targeted therapies to treat these conditions.
Product Name:
CSNK2A2 Rabbit Polyclonal Antibody
SKU:
CAB1616
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CSNK2A2 (NP_001887.1).
This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11.
Purification Method:
Affinity purification
Gene ID:
1459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSNK2A2 antibody (CAB1616) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
