The CSRNP1 Polyclonal Antibody (CAB7130) is a powerful tool for research involving the CSRNP1 protein, a transcription factor involved in cell proliferation, differentiation, and apoptosis. This polyclonal antibody, developed using rabbit immunization techniques, exhibits high specificity and sensitivity towards human samples and is optimized for Western blot applications.CSRNP1, also known as cysteine- and glycine-rich protein 1, has been implicated in a variety of cellular processes, including cell cycle regulation and DNA damage response pathways. Its role in promoting or inhibiting cell growth and survival makes it a promising target for investigating cancer biology and potential therapeutic interventions.
By utilizing the CSRNP1 Polyclonal Antibody, researchers can effectively detect and analyze the expression of CSRNP1 in various cell types, shedding light on its function in normal physiology and disease states. This antibody is a valuable asset for studies in oncology, molecular biology, and drug development, offering insights into the molecular mechanisms underlying cancer progression and treatment resistance.
Product Name:
CSRNP1 Rabbit Polyclonal Antibody
SKU:
CAB7130
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSRNP1 (NP_149016.2).
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64651
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CSRNP1 Rabbit pAb (CAB7130) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
