The CTBP1 Polyclonal Antibody (CAB14616) is a valuable tool for researchers studying CTBP1, a transcriptional corepressor involved in various cellular processes, including regulation of gene expression and cell cycle progression. This antibody, derived from rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in applications such as Western blotting.CTBP1, also known as C-terminal binding protein 1, is a key player in transcriptional repression and functions by recruiting histone deacetylases to target genes.
Dysregulation of CTBP1 has been implicated in several diseases, including cancer and metabolic disorders, making it an attractive target for therapeutic intervention.By utilizing the CTBP1 Polyclonal Antibody, researchers can gain valuable insights into the role of CTBP1 in various cellular pathways and diseases, ultimately advancing our understanding of its potential as a therapeutic target. Its versatility and reliability make it a valuable asset in studies focused on transcriptional regulation and disease mechanisms.
Product Name:
CtBP1 Rabbit Polyclonal Antibody
SKU:
CAB14616
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-353 of CtBP1 (NP_001319.1).
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using CtBP1 Rabbit pAb (CAB14616) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
