The CXCR4 Monoclonal Antibody (CAB19035) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications.CXCR4, a chemokine receptor, is involved in a wide range of biological processes, including cell signaling, adhesion, and migration. Dysregulation of CXCR4 has been linked to various diseases, such as cancer, HIV infection, and inflammatory disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CXCR4 Monoclonal Antibody
SKU:
CAB19035
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0381
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Cell Junction, Cell Membrane, Early Endosome, Late Endosome, Lysosome, Multi-Pass Membrane Protein.
Calculated MW:
40kDa
Observed MW:
43kDa
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method
Affinity purification
Gene ID
7852
RRID
AB_2862527
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from HeLa cells, using CXCR4 Rabbit mAb (CAB19035) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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