The DNAJC7 Antibody (CAB2780) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications, enabling reliable detection and analysis of DNAJC7 in a variety of cell types.DNAJC7 is a member of the Heat shock protein 40 (Hsp40) family, which plays a critical role in assisting in the folding of newly synthesized proteins and in the disaggregation of misfolded proteins. Dysregulation of DNAJC7 has been implicated in various diseases, including neurodegenerative disorders and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
DNAJC7 Antibody
SKU:
CAB2780
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
DJ11, DJC7, TPR2, TTC2, DNAJC7
Positive Sample:
A-431, 293T, K-562
Cellular Localization:
Cytoplasm, Nucleus, Cytoskeleton.
Calculated MW:
56kDa
Observed MW:
60kDa
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
7266
RRID
AB_2764622
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using DNAJC7 Rabbit pAb (CAB2780) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
