Anti-DNTTIP2 Antibody (CAB16120)

Antibody Name:	Anti-DNTTIP2 Antibody
Antibody SKU:	CAB16120
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DNTTIP2 (NP_055412.2).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	Mouse pancreas

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DNTTIP2 (NP_055412.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MVVT RSAR AKAS IQAA SAES SGQK SFAA NGIQ AHPE SSTG SDAR TTAE SQTT GKQS LIPR TPKA RKRK SRTT GSLP KGTE PSTD GETS EAES NYSV SEHH DTIL RVTR RRQI LIAC SPVS SVRK KPKV TPTK ESYT EEIV SEAE SHVS GISR IVLP TEKT TGAR RSKA KSLT DPSQ ESHT EAIS DAET SSSD ISFS GIAT RRTR SMQR KLKA QTEK KDSK IVPG NEKQ IVGT PVNS EDSD TRQT SHLQ ARSL SEIN KPNF YNND FDDD FSHR SSEN ILTV HEQA NVES LKET KQNC KDLD
Gene ID:	30836
Uniprot:	Q5QJE6
Cellular Location:	Nucleus
Calculated MW:	84kDa
Observed MW:	105kDa

Synonyms:	DNTTIP2, ERBP, FCF2, HSU15552, LPTS-RP2, TdIF2
Background:	This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease.

UniProt Protein Function:	ERBP: Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein.
UniProt Protein Details:	Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1p22.1 Cellular Component: nucleolus; nucleus Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
NCBI Summary:	This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]
UniProt Code:	Q5QJE6
NCBI GenInfo Identifier:	54633315
NCBI Gene ID:	30836
NCBI Accession:	NP_055412.2
UniProt Secondary Accession:	Q5QJE6,Q12987, Q53H59, Q5TFJ4, Q6TLI0, Q76MJ8, Q86WX9
UniProt Related Accession:	Q5QJE6
Molecular Weight:	84,469 Da
NCBI Full Name:	deoxynucleotidyltransferase terminal-interacting protein 2
NCBI Synonym Full Names:	deoxynucleotidyltransferase, terminal, interacting protein 2
NCBI Official Symbol:	DNTTIP2
NCBI Official Synonym Symbols:	ERBP; FCF2; TdIF2; HSU15552; LPTS-RP2
NCBI Protein Information:	deoxynucleotidyltransferase terminal-interacting protein 2
UniProt Protein Name:	Deoxynucleotidyltransferase terminal-interacting protein 2
UniProt Synonym Protein Names:	Estrogen receptor-binding protein; LPTS-interacting protein 2; LPTS-RP2; Terminal deoxynucleotidyltransferase-interacting factor 2; TdIF2; TdT-interacting factor 2
Protein Family:	Deoxynucleotidyltransferase terminal-interacting protein
UniProt Gene Name:	DNTTIP2
UniProt Entry Name:	TDIF2_HUMAN

	Western blot analysis of extracts of mouse pancreas, using DNTTIP2 antibody (CAB16120) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
	Immunofluorescence analysis of U-2 OS cells using DNTTIP2 antibody (CAB16120) at dilution of 1:100. Blue: DAPI for nuclear staining.

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)