The EDC3 Antibody (CAB13763) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EDC3 protein, this antibody allows for the detection and analysis of EDC3 in various cell types, making it a valuable resource for studies in RNA biology and gene expression regulation. EDC3 is a crucial component of RNA processing complexes, contributing to mRNA decay and quality control mechanisms in the cell. Dysregulation of EDC3 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular homeostasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
EDC3 Antibody
SKU:
CAB13763
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
YJDC, LSM16, MRT50, YJEFN2, hYjeF_N2-15q23, EDC3
Positive Sample:
U-87MG, MCF7, HeLa, Mouse pancreas
Cellular Localization:
Cytoplasm, P-Body.
Calculated MW:
56kDa
Observed MW:
56kDa
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
Purification Method
Affinity purification
Gene ID
80153
RRID
AB_2760621
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EDC3 Rabbit pAb (CAB13763) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
