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Anti-EFHD2 Antibody (CAB14926)

SKU:
CAB14926
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 2 Anti-EFHD2 Antibody CAB14926
  • Signal Transduction Antibodies 2 Anti-EFHD2 Antibody CAB14926
  • Signal Transduction Antibodies 2 Anti-EFHD2 Antibody CAB14926
  • Signal Transduction Antibodies 2 Anti-EFHD2 Antibody CAB14926
€139 - €419
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Description

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Antibody Name:Anti-EFHD2 Antibody
Antibody SKU:CAB14926
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATD ELAT KLSR RLQM EGEG GGET PEQP GLNG AAAA AAGA PDEA AEAL GSAD CELS AKLL RRAD LNQG IGEP QSPS RR
Gene ID:79180
Uniprot:Q96C19
Cellular Location:Membrane raft
Calculated MW:26kDa
Observed MW:27kDa
Synonyms:EFHD2, SWS1
Background:
UniProt Protein Function:EFHD2: May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: lipid raft

Molecular Function:calcium ion binding

UniProt Code:Q96C19
NCBI GenInfo Identifier:20149675
NCBI Gene ID:79180
NCBI Accession:NP_077305
UniProt Secondary Accession:Q96C19,Q9D8Y0,
UniProt Related Accession:Q96C19
Molecular Weight:26,697 Da
NCBI Full Name:EF-hand domain-containing protein D2
NCBI Synonym Full Names:EF-hand domain family, member D2
NCBI Official Symbol:EFHD2  
NCBI Official Synonym Symbols:SWS1  
NCBI Protein Information:EF-hand domain-containing protein D2; swiprosin 1; swiprosin-1; EF hand domain containing 2; EF hand domain family, member D2
UniProt Protein Name:EF-hand domain-containing protein D2
UniProt Synonym Protein Names:Swiprosin-1
Protein Family:Zinc finger SWIM domain-containing protein
UniProt Gene Name:EFHD2  
UniProt Entry Name:EFHD2_HUMAN
Anti-EFHD2 Antibody (CAB14926)Western blot analysis of extracts of mouse lung, using EFHD2 antibody (CAB14926) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-EFHD2 Antibody (CAB14926)Immunohistochemistry of paraffin-embedded human tonsil using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens).
Anti-EFHD2 Antibody (CAB14926)Immunohistochemistry of paraffin-embedded human appendix using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens).
Anti-EFHD2 Antibody (CAB14926)Immunohistochemistry of paraffin-embedded mouse spleen using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens).

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