Efimosfermin Alfa (Research-Grade) is a research-grade biosimilar antibody targeting FGF21. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Fibroblast growth factor 21 (FGF21) is a ~22 kDa protein. Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Product Name:
Efimosfermin Alfa (Research-Grade)
SKU:
GXBS02352
Size:
100 µg, 1 mg
Target:
FGF21
Isotype:
Fc fragment of human immunoglobulin G1 fused via peptide linker to human FGF-21 fragment-variant
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
2765640-39-7
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Humanized IgG1-kappa anti-human TCR Vβ6/β10 monomer disulfide bridged to human IL-2 fragment fused via (G4S)2 peptide linker to immunoglobulin G1 Fc fragment.
