Description
Elk3 (Phospho-Ser357)Transcription Factor Activity Assay
The Elk3 Phospho-Ser357 Transcription Factor Activity Assay offered by AssayGenie is a cutting-edge tool for studying the activity of the Elk3 transcription factor. This assay is designed for accurate detection of Elk3 activity in cell lysates and tissue samples, providing researchers with valuable insights into the role of Elk3 in gene regulation.Elk3 is a transcription factor that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of Elk3 at Ser357 has been shown to modulate its transcriptional activity, making this site a key regulator of Elk3 function.
With its high sensitivity and specificity, the Elk3 Phospho-Ser357 Transcription Factor Activity Assay delivers reliable and reproducible results, making it an essential tool for studying Elk3 signaling pathways and identifying potential therapeutic targets for diseases such as cancer and cardiovascular disorders. Trust AssayGenie for all your research needs and unlock the potential of Elk3 in your studies.
| Product Name: | Elk3 (Phospho-Ser357)Transcription Factor Activity Assay |
| Product Code: | TFAB00024 |
| Target: | Elk3 (Phospho-Ser357) |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie Elk3 (Phospho-Ser357) transcription factor activity assay allows for the detection and qualitative analysis of Elk3 (Phospho-Ser357) active transcription factors in eukaryotic nuclear or cell lysates.
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | ELK3: a transcription factor of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. May be a negative regulator of transcription but can activate transcription when co expressed with Ras, Src or Mos. Activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 12q23 Cellular Component: intracellular membrane-bound organelle; mitochondrion; nucleoplasm; nucleus Molecular Function:protein binding; purine-rich negative regulatory element binding; transcription corepressor activity Biological Process: cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction |
| NCBI Summary: | This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | P41970 |
| NCBI GenInfo Identifier: | 116241349 |
| NCBI Gene ID: | 2004 |
| NCBI Accession: | P41970.2 |
| UniProt Secondary Accession: | P41970,Q6FG57, Q6GU29, Q9UD17, B2R6S6, |
| UniProt Related Accession: | P41970,AAB34628 |
| Molecular Weight: | 44,240 Da |
| NCBI Full Name: | ETS domain-containing protein Elk-3 |
| NCBI Synonym Full Names: | ELK3, ETS transcription factor |
| NCBI Official Symbol: | ELK3 |
| NCBI Official Synonym Symbols: | ERP; NET; SAP2; SAP-2 |
| NCBI Protein Information: | ETS domain-containing protein Elk-3 |
| UniProt Protein Name: | ETS domain-containing protein Elk-3 |
| UniProt Synonym Protein Names: | ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2 |
| Protein Family: | ETS domain-containing protein |
| UniProt Gene Name: | ELK3 |
| UniProt Entry Name: | ELK3_HUMAN |
