Elk3 (Phospho-Ser357) Transcription Factor Activity Assay

Product Name:	Elk3 (Phospho-Ser357) Transcription Factor Activity Assay
Product Code:	TFAB00024
Target:	Elk3 (Phospho-Ser357)
Reactivity:	Human, Mouse, Rat
Sample Types:	Nuclear or cell lysates

The Assay Genie Elk3 (Phospho-Ser357) transcription factor activity assay allows for the detection and qualitative analysis of Elk3 (Phospho-Ser357) active transcription factors in eukaryotic nuclear or cell lysates.

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:	4.5 hours
Detection Method:	Colorimetric 450 nm
Size:	12 x 8-Well Microstrips
Storage:	4°C for 6 months

UniProt Protein Function:	ELK3: a transcription factor of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. May be a negative regulator of transcription but can activate transcription when co expressed with Ras, Src or Mos. Activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
UniProt Protein Details:	Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 12q23 Cellular Component: intracellular membrane-bound organelle; mitochondrion; nucleoplasm; nucleus Molecular Function:protein binding; purine-rich negative regulatory element binding; transcription corepressor activity Biological Process: cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction
NCBI Summary:	This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
UniProt Code:	P41970
NCBI GenInfo Identifier:	116241349
NCBI Gene ID:	2004
NCBI Accession:	P41970.2
UniProt Secondary Accession:	P41970,Q6FG57, Q6GU29, Q9UD17, B2R6S6,
UniProt Related Accession:	P41970,AAB34628
Molecular Weight:	44,240 Da
NCBI Full Name:	ETS domain-containing protein Elk-3
NCBI Synonym Full Names:	ELK3, ETS transcription factor
NCBI Official Symbol:	ELK3
NCBI Official Synonym Symbols:	ERP; NET; SAP2; SAP-2
NCBI Protein Information:	ETS domain-containing protein Elk-3
UniProt Protein Name:	ETS domain-containing protein Elk-3
UniProt Synonym Protein Names:	ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2
Protein Family:	ETS domain-containing protein
UniProt Gene Name:	ELK3
UniProt Entry Name:	ELK3_HUMAN

Antibodies

Phospho-ELK3 (S357) Antibody (PACO02640)

ELK3 Antibody (PACO03611)

ELK3 Antibody (PACO55470)

ELK3 Antibody, HRP conjugated (PACO55471)

ELK3 Antibody, FITC conjugated (PACO55472)