Anti-ELOVL3 Antibody [V61P2B3-D10]

ELOVL3 Antibody [V61P2B3-D10]

ELOVL3 Antibody [V61P2B3-D10] is a mouse monoclonal antibody directed against ELOVL3, offered by Assay Genie for research applications. Reported applications include WB, IHC and ELISA. Reported reactivity: Human and Rat. Supplied as IgG1, purified by Protein G.

ELOVL3 (Elongation of Very Long Chain Fatty Acids Protein 3) is a member of the ELOVL family of enzymes responsible for the biosynthesis of very long-chain saturated and monounsaturated fatty acids. These lipids are essential components of neuronal membranes, myelin sheaths, and signaling molecules that maintain brain structure and function. In the context of neurodegenerative diseases, ELOVL3 has emerged as a key regulator of lipid homeostasis. Altered expression or activity of ELOVL3 may disrupt membrane integrity, impair synaptic transmission, and contribute to neuroinflammation—hallmarks of conditions such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Its role in generating specific lipid species also implicates ELOVL3 in modulating oxidative stress and mitochondrial function, both of which are critical in neuronal survival and aging. Recent studies suggest that ELOVL3 may influence glial cell behavior and neuroimmune interactions, positioning it as a potential biomarker for disease progression and a target for lipid-based therapeutic strategies. As lipid metabolism gains prominence in neuroscience, ELOVL3 offers a unique window into the intersection of metabolic regulation and neurodegeneration. Understanding ELOVL3’s function in the brain could unlock new approaches to preserving neuronal integrity and combating age-related cognitive decline. This antibody is also available conjugated to ATTO 390, ATTO 488, ATTO 594, APC, Biotin, FITC, HRP, PerCP and RPE. Supplied in 100 µg. For research use only; not for diagnostic or therapeutic procedures.