Fbxw10 Antibody (PACO49206)
- SKU:
- PACO49206
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Fbxw10 Antibody (PACO49206) |
Antibody SKU: | PACO49206 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Mouse |
Immunogen: | Recombinant Mouse F-box/WD repeat-containing protein 10 protein (701-1030AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity). |
Synonyms: | F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10), Fbxw10 |
UniProt Protein Function: | FBXW10: Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11|11 B2Molecular Function: ubiquitin-protein ligase activity |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q5SUS0 |
NCBI GenInfo Identifier: | 81910136 |
NCBI Gene ID: | 213980 |
NCBI Accession: | Q5SUS0.1 |
UniProt Secondary Accession: | Q5SUS0,Q5U4G1 |
UniProt Related Accession: | Q5SUS0 |
Molecular Weight: | 53.16 kDa |
NCBI Full Name: | F-box/WD repeat-containing protein 10 |
NCBI Synonym Full Names: | F-box and WD-40 domain protein 10 |
NCBI Official Symbol: | Fbxw10Â Â |
NCBI Official Synonym Symbols: | HREP; Fbw10; SM25H2; SM2SH2Â Â |
NCBI Protein Information: | F-box/WD repeat-containing protein 10 |
UniProt Protein Name: | F-box/WD repeat-containing protein 10 |
UniProt Synonym Protein Names: | F-box and WD-40 domain-containing protein 10 |
Protein Family: | F-box/WD repeat-containing protein |
UniProt Gene Name: | Fbxw10Â Â |
UniProt Entry Name: |