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Anti-FCGR1A Antibody (CAB1197)

SKU:
CAB1197
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-FCGR1A Antibody CAB1197
  • Immunology Antibodies 1 Anti-FCGR1A Antibody CAB1197
  • Immunology Antibodies 1 Anti-FCGR1A Antibody CAB1197
€139 - €419
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Description

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Antibody Name:Anti-FCGR1A Antibody
Antibody SKU:CAB1197
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-292 of human FCGR1A (NP_000557.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, U-937, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-292 of human FCGR1A (NP_000557.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SPLL EGNL VTLS CETK LLLQ RPGL QLYF SFYM GSKT LRGR NTSS EYQI LTAR REDS GLYW CEAA TEDG NVLK RSPE LELQ VLGL QLPT PVWF H
Gene ID:2209
Uniprot:P12314
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:38kDa/42kDa
Observed MW:70-80kDa
Synonyms:FCGR1A, CD64, CD64A, FCRI, IGFR1
Background:This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
UniProt Protein Function:FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.2-q21.3

Cellular Component: early endosome membrane; plasma membrane; integral to membrane

Molecular Function:protein binding; IgG binding; receptor signaling protein activity

Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; signal transduction; phagocytosis, engulfment

NCBI Summary:This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
UniProt Code:P12314
NCBI GenInfo Identifier:50403717
NCBI Gene ID:2209
NCBI Accession:P12314.2
UniProt Related Accession:P12314
Molecular Weight:
NCBI Full Name:High affinity immunoglobulin gamma Fc receptor I
NCBI Synonym Full Names:Fc fragment of IgG receptor Ia
NCBI Official Symbol:FCGR1A  
NCBI Official Synonym Symbols:CD64; FCRI; CD64A; IGFR1  
NCBI Protein Information:high affinity immunoglobulin gamma Fc receptor I
UniProt Protein Name:High affinity immunoglobulin gamma Fc receptor I
UniProt Synonym Protein Names:Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64
UniProt Gene Name:FCGR1A  
UniProt Entry Name:FCGR1_HUMAN
Anti-FCGR1A Antibody (CAB1197)Western blot analysis of extracts of various cell lines, using FCGR1A antibody (CAB1197) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
Anti-FCGR1A Antibody (CAB1197)Immunohistochemistry of paraffin-embedded rat kidney using FCGR1A Rabbit pAb (CAB1197) at dilution of 1:100 (40x lens).
Anti-FCGR1A Antibody (CAB1197)Immunohistochemistry of paraffin-embedded mouse kidney using FCGR1A Rabbit pAb (CAB1197) at dilution of 1:100 (40x lens).

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