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FITC Anti-Mouse TCR κ/δ Antibody [GL3] (AGEL3300)

Datasheet MSDS
SKU AGEL3300
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Armenian Hamster
Isotype Armenian Hamster IgG
Clone GL3
Conjugation FITC
$149 - $376

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Description

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FITC Anti-Mouse TCR γ/δ Antibody [GL3]

The FITC Anti-Mouse TCR Antibody (GL3) is a high-quality reagent offered by AssayGenie for research applications involving the T cell receptor (TCR) in mouse models. This antibody is specifically designed for recognition of the mouse TCR, a crucial component of the immune system responsible for recognizing antigens presented by major histocompatibility complex (MHC) molecules.Developed for fluorescence studies, the FITC-conjugated GL3 antibody enables visualization and analysis of TCR expression and localization within cells. Its high specificity and sensitivity make it ideal for flow cytometry and immunofluorescence techniques, allowing researchers to investigate TCR dynamics in different cell populations under various experimental conditions.

The GL3 antibody's reliable performance and consistency in experimental settings ensure accurate and reproducible results, making it a valuable tool for immunologists, cell biologists, and researchers studying immune responses, infection, and autoimmunity in mouse models. With its ability to target and detect the mouse TCR, the FITC Anti-Mouse TCR Antibody (GL3) from AssayGenie is a trusted reagent for advancing research in immunology and related fields.

Product Title:FITC Anti-Mouse TCR γ/δ Antibody [GL3]
SKU:AGEL3300
Size:25µg, 100µg
Clone No:GL3
Synonyms:T cell receptor γ/δ;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:110066,110067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.
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