UniProt Protein Function: | FLRT1: May have a function in cell adhesion and/or receptor signaling.Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integralChromosomal Location of Human Ortholog: 11q13.1Cellular Component: cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; extracellular space; focal adhesion; integral to plasma membrane; intercellular junction; perinuclear region of cytoplasm; proteinaceous extracellular matrixMolecular Function: fibroblast growth factor receptor binding; protein binding, bridging; protein kinase inhibitor activity; receptor signaling protein activityBiological Process: cell adhesion; cytokine and chemokine mediated signaling pathway; dendrite development; fibroblast growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity; positive regulation of synaptogenesis |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NZU1 |
NCBI GenInfo Identifier: | 34577057 |
NCBI Gene ID: | 23769 |
NCBI Accession: | NP_037412.2 |
UniProt Secondary Accession: | Q9NZU1,Q8WVA2 |
UniProt Related Accession: | Q9NZU1 |
Molecular Weight: | |
NCBI Full Name: | leucine-rich repeat transmembrane protein FLRT1 |
NCBI Synonym Full Names: | fibronectin leucine rich transmembrane protein 1 |
NCBI Official Symbol: | FLRT1Â Â |
NCBI Official Synonym Symbols: | SPG68Â Â |
NCBI Protein Information: | leucine-rich repeat transmembrane protein FLRT1 |
UniProt Protein Name: | Leucine-rich repeat transmembrane protein FLRT1 |
UniProt Synonym Protein Names: | Fibronectin-like domain-containing leucine-rich transmembrane protein 1 |
Protein Family: | Leucine-rich repeat transmembrane protein |
UniProt Gene Name: | FLRT1Â Â |
UniProt Entry Name: | FLRT1_HUMAN |