Description

GenieFluor 488 Anti-Human CD58 Antibody [TS2/9.1]

The GenieFluor™ 488 Anti-Human CD58 Antibody (TS2/9) is a powerful tool for researchers studying immune cell interactions and signaling pathways. This highly specific antibody binds to the CD58 protein, also known as LFA-3, which plays a crucial role in T-cell activation and adhesion.Developed for use in flow cytometry, immunofluorescence, and immunohistochemistry applications, the GenieFluor™ 488 Anti-Human CD58 Antibody (TS2/9) offers exceptional sensitivity and specificity in detecting CD58 expression on the surface of human cells. Its bright fluorescence signal allows for precise visualization and quantification of CD58 levels, facilitating detailed analyses of cell-to-cell interactions and immune responses.

With its validated performance in various experimental settings, this antibody is an essential tool for researchers investigating immune system function, autoimmune diseases, transplant rejection, and cancer immunotherapy. By targeting CD58, researchers can gain deeper insights into the mechanisms underlying immune cell communication and potentially uncover new therapeutic strategies for manipulating immune responses.Enhance your research capabilities and explore the intricate world of immune cell biology with the GenieFluor™ 488 Anti-Human CD58 Antibody (TS2/9).

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Product Title:	GenieFluor 488 Anti-Human CD58 Antibody [TS2/9.1]
SKU:	AGEL3088
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	TS2/9.1
Synonyms:	Lymphocyte function-associated antigen 3;CD58;Ag3;Surface glycoprotein LFA-3;LFA3;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	Genie Fluor488
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P19256
Gene ID:	965
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.

GenieFluor 488 Anti-Human CD58 Antibody [TS2/9.1] (AGEL3088)

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Description