Anti-GP2 Antibody (CAB6378)
- SKU:
- CAB6378
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-GP2 Antibody (CAB6378) |
| Antibody SKU: | CAB6378 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-251MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CSSI LQTE ERNW VSVT SPVQ ASAC RNIL ERNQ THAI YKNT LSLV NDFI IRDT ILNI NFQC AYPL DMKV SLQA ALQP IVSS LNVS VDGN GEFI VRMA LFQD QNYT NPYE GDAV ELSV ESVL YVGA ILEQ GDTS RFNL VLRN CYAT PTED KADL VKYF IIRN SCSN QRDS TIHV EENG QSSE SRFS VQMF MFAG HYDL VFLH CEIH LCDS LNEQ CQPS CSRS QVRS EVPA IDLA RVLD LGPI TRRG AQSP GVMN GTPS TAGF LVAW PMVL LTVL LAWL F |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Secreted |
| Calculated MW: | 43kDa/59kDa |
| Observed MW: | 55kDa |
| Synonyms: | GP2, ZAP75 |
| Background: | This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. |
 | Western blot analysis of extracts of U-251MG cells, using GP2 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. |
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