The GSTA1 Antibody (CAB1628) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, has high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By binding to the GSTA1 protein, researchers can analyze and detect its expression in various cell types, aiding in studies related to drug metabolism, oxidative stress, and cancer research.GSTA1 is a critical enzyme belonging to the glutathione S-transferase family, known for its role in protecting cells from oxidative damage and maintaining cellular homeostasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
GSTA1 Antibody
SKU:
CAB1628
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GST2, GTH1, GSTA1-1, GST-epsilon, GSTA1
Positive Sample:
HepG2, Rat liver
Cellular Localization:
Cytoplasm.
Calculated MW:
26kDa
Observed MW:
26kDa
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
2938
RRID
AB_2763688
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using GSTA1 Rabbit pAb (CAB1628) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
