Anti-USH1C Antibody (CAB4368)
- SKU:
- CAB4368
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- USH1C
- AIE-75
- DFNB18
- DFNB18A
- NY-CO-37
- NY-CO-38
- PDZ-45
- PDZ-73
- PDZ-73/NY-CO-38
- PDZ73
- PDZD7C
- ush1cpst
- harmonin
Frequently bought together:
Description
| Product Name: | USH1C Rabbit pAb |
| Product Code: | CAB4368 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | USH1C, AIE-75, DFNB18, DFNB18A, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, PDZ73, PDZD7C, ush1cpst, harmonin |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of zebrafish USH1C (NP_001035018.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, Mouse kidney, Mouse small intestine, Rat testis, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of zebrafish USH1C (NP_001035018.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MERK VARE FRHK VELL IDNE AEKD YLYD VLRM YHQS MDLP VLVG DLKL VINE PKRL PLFD AIRP LIPL KHQV QYDQ LTPK RSRK LKEV RLDR THPE GLGL |
| Gene ID: | 564412 |
| Cellular Location: | Cytoplasm, cytoskeleton, cytosol |
| Calculated MW: | 45kDa/58kDa/60kDa/62kDa/101kDa |
| Observed MW: | 73kDa |
| Background: | This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. |
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