The HOXA13 Antibody (CAB9822) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, allowing for precise detection in various experimental settings.HOXA13 is known to play a vital role in embryonic development, particularly in the formation of the limbs and genitalia. Dysregulation of HOXA13 has been linked to developmental abnormalities and diseases such as hand-foot-genital syndrome. Therefore, understanding the function and expression of HOXA13 is crucial for uncovering its potential roles in various physiological and pathological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
HOXA13 Antibody
SKU:
CAB9822
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HOX1, HOX1J, HOXA13
Positive Sample:
Mouse liver, Mouse skeletal muscle, Rat liver, Rat skeletal muscle
Cellular Localization:
Nucleus.
Calculated MW:
40kDa
Observed MW:
38kDa
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Purification Method
Affinity purification
Gene ID
3209
RRID
AB_2769827
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using HOXA13 Rabbit pAb (CAB9822) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
