The HOXA13 Monoclonal Antibody (CAB9564) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.HOXA13 is known for its role in regulating gene expression and cell fate determination, particularly in the development of various tissues and organs. Studies have linked dysregulation of HOXA13 to developmental disorders, cancer, and other diseases, highlighting the importance of understanding its function and activity.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
HOXA13 Monoclonal Antibody
SKU:
CAB9564
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1636
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HOX1, HOX1J, HOXA13
Positive Sample:
HeLa, 293T, Hep G2, Mouse liver, Mouse spleen, Mouse kidney, Rat liver
Cellular Localization:
Nucleus.
Calculated MW:
40kDa
Observed MW:
45kDa
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Purification Method
Affinity purification
Gene ID
3209
RRID
AB_2863725
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using HOXA13 Rabbit mAb (CAB9564) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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